Up until two minutes ago, you could have won money from me by betting that I could not correctly spell barbiturates.
I have gone my whole life unaware of the second R. I certainly don't pronounce it, and my aural memory is that no one else does, either. (Am I wrong about this? (too?))
In case you're wondering, no, I don't say "Feb-yoo-ary," but I might have to stop getting so irritated at people who do.
But "nuke-yoo-ler" is still right out.
And no, I am not contemplating a change in my chemical intake, either. I'd explain the context in which the word came up, but I think I have already written the most boring blog post on the Internet.